BDBM13080 CGS 27023A Analog 3::N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sulfonamido]acetamide::US20230357139, Compound A::US20240050571, Compound NNGH

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO

InChI Key InChIKey=JIRXORZYIXSWOB-UHFFFAOYSA-N

Data  9 KI  27 IC50

PDB links: 10 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13080   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataKi:  132nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataKi:  133nM ΔG°:  -9.75kcal/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair